Signs of implantation after IUI – The signs of implantation can be subtle and confusing. Some women become pregnant without experiencing any implantation symptoms, and to muddy the water further, these symptoms can be mimicked by early menstruation or even side effects of the IUI procedure itself.
Spotting: When the blastocyst implants, some uterine cells are dislodged from the lining. When you miss your period, these few dislodged cells may sometimes be discharged and appear as slight spotting. Implantation spotting will usually be pinking or light brown rather than bright red as with a period. This is usually a very minimal amount of blood and is easy to miss or confuse with a very light period. If you do experience spotting, there’s also a chance it was caused by the IUI catheter.
Cramping: This is the most common of all the implantation signs, but is still only reported by 30 to 35% of women who conceive. Slight crampy twinges or a feeling of fullness in the abdomen could be a sign of implantation, it may be a sign of impending menstruation, or it could be caused by the IUI procedure. Some women describe the feeling of implantation cramping as pinching or tingling below the navel, or as slight gas pains.
The only way to be sure whether or not IUI has worked is to take a pregnancy test 14 days after the IUI procedure. Some women opt to take home pregnancy tests earlier than this, which can be somewhat stressful. It is not easy to get a reliable result before 14 days.
- The trigger shot used to stimulate ovulation can cause false positives for days after the IUI, and tests in the days after can give false negatives, because there has not been enough time for pregnancy hormones to build up to detectable levels in the urine.
- This can create a rollercoaster of anxiety at a time where staying as relaxed as possible is important.
As much as possible, lean on your support system and practice extra self-care during this time. Try to put off home testing as long as you can: when the two weeks is up, you will return to the clinic for a blood test, which will give you an accurate answer to the question of whether you’re pregnant. 
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Contents
How many days after an IUI can I take a pregnancy test?
– The two week wait (TWW) after an IUI can be excruciatingly difficult, but it’s worth it to avoid potential false positives and false negatives on home pregnancy tests. Follow your clinic’s instructions and wait at least 14 days post-IUI before taking a test.
- Many clinics will schedule you for a pregnancy blood test at the 14-day mark.
- A blood test can detect lower levels of hCG and is considered even more accurate than urine tests.
- Hang in there.
- We see you, and we know how eager you are to see that positive.
- If you must take a test before your TWW is up, know that we totally understand.
Just don’t put all your hope or despair in what you see, and test again when your doctor tells you to.
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Can you get a positive pregnancy test 3 days after IUI?
After an IUI procedure, you have to wait at least two weeks to see if you have conceived. Even though it’s incredibly hard to wait, checking too early with an at-home pregnancy test can generate a false-negative result because pregnancy hormone levels are not yet high enough to measure.
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Is IUI successful in first cycle?
IUI Success Rates after Multiple Cycles – With natural conception, we tend to look at success over 6 months to a year of trying repeatedly month after month. That’s why fertility specialists suggest couples under the age of 35 try for 12 months on their own and couples over the age of 35 try for 6 months before seeking fertility assistance (less for women over 35 because as women age, it’s more important they seek help sooner).
It’s the repetition that ensures success. This is somewhat true of IUI as well, but only up to a certain point. Statistics show that the majority of IUI pregnancies occur in the first three to four cycles of IUI. One study concluded that 88% of all successful IUIs happen within three cycles and 95% within four.
Another study found that 90% of IUI pregnancies occur in the first three cycles of IUI. Knowing when to move on to more advanced treatment like IVF is important for your emotional and financial well-being. If after 3-4 IUIs you have not been successful, success rates flatten out and it is statistically unlikely to work for you. 
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Why IUI is not successful in first attempt?
Question: Why does IUI fail? – Answer: There are several reasons behind the failure of IUI. Some of the common reasons for failed IUI are endometriosis, poor sperm quality, decreased ovarian reserve, poor egg quality, etc.
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What happens every day after IUI?
– Many women experience cramping during or after an IUI. This is very common, and can be caused by the following:
Cramping during the IUI usually happens as the catheter is being passed through the cervix, and while the sperm is being injected. This cramp is usually pretty short-lived. It should go away as soon as the doctor removes the catheter. Some women experience cramping after IUI. The catheter can sometimes irritate the uterus, which can cause mild cramping, too. Ovulation can also cause abdominal cramping. If you’re ovulating multiple follicles, usually from taking medication to induce ovulation, this may worsen ovulation pain or cramping.Cramping a few days after the IUI can sometimes signal implantation, or it can signal that your body’s getting ready for your period. It doesn’t mean that you definitely are, or aren’t, pregnant.
What’s a good follicle size for IUI?
Table 4 – Varimax-rotated component matrix of the PCA
| Component | ||||
|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |
| Age | 0.094 | −0.133 | 0.821 | 0.049 |
| NF | 0.952 | −0.214 | −0.130 | 0.010 |
| ET | −0.022 | 0.852 | −0.068 | 0.040 |
| LH | −0.008 | 0.369 | −0.147 | 0.798 |
| RFS | 0.447 | −0.512 | −0.563 | 0.174 |
| LFS | 0.769 | 0.280 | 0.421 | −0.157 |
| TMF | −0.065 | −0.382 | 0.152 | 0.734 |
| Eigenvalue | 1.712 | 1.412 | 1.235 | 1.235 |
| Percent variance | 24.452 | 20.173 | 17.649 | 17.638 |
| Cumulative variance | 24.452 | 44.625 | 62.273 | 79.912 |
Only cases for which outcome positives are used in the analysis phase. Note: Only cases for which outcome positives are used in the analysis phase. NF number of follicle, ET endometrium thickness, LH luteinizing hormone, RFS right follicle size, LFS left follicle size, TMF total motile fraction With the age as a factor, it was seen that females presenting their fertility status were of age 20–44 years, patients beyond the age of 40 years had no positive outcome.
- Not surprisingly, in the age group 20–24 years, the pregnancy rate after an IUI protocol was higher than those of other age groups.
- The positive outcome was evident in the range of 5–12 mm ET; specifically, 17 patients with ET 10 IU/mL had negative outcome.
- The maximum pregnancy rate, 42.5 % was observed in women with LH concentration between 4.1 and 6.0 IU/mL.
It was seen that participants with one and two dominant follicle(s) in an ovary had the positive outcome at 11.4 and 22.5 %, respectively. Patients with follicular size between 14 and 22 mm had the positive outcome. However, the maximum pregnancy rate, 62.5 % was observed in the group with follicular size, 14.1–16.0 mm (Table 1 ).
The positive outcome was observed with TMF values, 5.1–20.0 million. TMF values less than 5 and greater than 20 million had the negative outcome. However, on evaluating the TMF, the highest pregnancy rate was observed with a range of 8–11 million sperm count (Table 2 ). The PCA of the dataset revealed that all the factors: female-age, LH, NF, LFS, RFS, ET, and TMF were found to have determinative roles, and their co-relation patterns for the positive outcome were elucidated (Table 3 ).
Only four components could be extracted from the analysis, with eigen values, 1.712, 1.412, 1.235, and 1.235, which were more than 1.0; in other words, components with eigen values less than 1.0 were ignored. Among them, the component 1 was of the highest eigen value, 1.712, and the highest percent variance, 24.452; but the highest cumulative variance, 79.912 was found in the component 4 (Table 4 ).
Positive values in the correlation matrix signify association of the factors, while negative values do not; for example, with the age factor—factors NF, LFS and TMF are correlated, but ET, LH and RFS are not correlated (Table 3 ). It was evident that with the age parameter, three factors: NF, LFS, and RFS were related as the component 1.
Similarly, in the component 2, ET, LH, and LFS were related; in the component 3, age, LFS, and TMF were related; in the component 4, age NF, ET, LH, RFS, and TMF were related. The component 1 with the highest eigen value signifies that the associated factors were highly related to themselves than those of the component 2 with a lower eigen value.
- Similarly, the associated factors of the component 2 were highly related to themselves than with those of the component 3, and so on for the other components 3 and 4 with the progressively lower eigen value of 1.235.
- Not surprisingly perhaps, the age factor was related by 1.8 % to NF; among them, LFS was highly related, i.e., 19.4 % to the age factor, whereas TMF was the least related with 1.5 % only.
Further, NF was related with three factors: RFS by 59.1, LFS by 58.9, and TMF by 0.4 %. Moreover, ET was related with LFS by 9.5 %, with TMF by 19.2 %, and with LH by 18.2 %. In a unifying narrative, it could be recorded that LH was related with RFS by 1.9 % and to TMF by 20.2 %.
- RFS was related with TMF by 12.9 % only; all factors were related to age (Table 3 ).
- All the cited threadbare infertility factors could be analyzed with digital values of co-relation for the positive outcome.
- From PCA-associated ANOVA results, it was ascertained that the age factor had a p -value, 0.012 (highly significant).
Similarly, NF had p = 0.005 (more highly significant), ET had p = 0.137 (highly insignificant), RFS had p = 0.239 (highly insignificant), LFS had p = 0.041 (significant), and TMF had p = 0.61 (highly insignificant), as significant values for the positive outcome (Table 5 ).
From the Table 5, it is discernible that RFS and TMF had highly insignificant values, while age, NF, and ET were moderately significant; clearly, LH value with the p -value of 0.0001 was signifying an absolute dependency for success. Moreover, a pregnancy rate per cycle of 17.33 % (52/300) was obtained in which, 15.38 % (8/52) were twins.
No major congenital anomaly was recorded, or were there any multiple pregnancies.
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How many attempts does IUI take?
When you should stop trying IUI and switch to IVF ? – IUI in general is the first line of treatment suggested to those who want to conceive as it is less invasive and more affordable. But what if no pregnancy occurs after several attempts of IUI? How many times should you try to conceive via IUI before moving on to IVF? This is a situation that many couples face while trying to become pregnant using this fertility treatment.
- The fact is that you may probably need to undergo 3-4 at-tempts before you successfully get pregnant, although some women will conceive in their first attempt itself.
- If you are under 35 years of age, most doctors will suggest 3 to 6 cycles of IUI before moving to IVF.
- However for those who are above 35 years of age, the chances of you conceiving through IUI may be less.So if you are above 35 years of age you must consult a fertility expert to check which option is best for you.
Additionally, it is best to consult with your doctor and part-ner about the number of attempts that you can go for.
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